Administrative information

  • Funding: Bulgarian National Science Fund, COST-related project support
  • Project identifier: КП-06-КОСТ/10.6.2026 г.
  • Project title: In vitro assessment of the impact of persistent organic pollutants from flue gases and atmospheric aerosols
  • Project leader: Prof. Tsveta Georgieva
  • Contracting institution: National Center of Public Health and Analyses
  • MU OmicsLab contribution: Assoc. Prof. Yordan Yordanov, PhD
  • Documented reporting period: 15 April 2026 - 31 July 2026

Summary

The project studies the biological impact of persistent organic pollutants associated with flue gases and atmospheric aerosols. The experimental direction combines in vitro toxicology with molecular readouts, while the computational component supports interpretation of transcriptomic data and selection of candidate markers for follow-up validation.

This work strengthens the link between environmental exposure toxicology, omics-based analysis, and reproducible bioinformatics within the wider MU OmicsLab research direction.

MU OmicsLab contribution

MU OmicsLab contributes to:

  • preparation of toxicological in vitro analyses using adherent cell culture models
  • preparation of bulk RNA-seq studies based on total RNA sequencing
  • transcriptomic analysis for prioritizing candidate markers for qPCR follow-up
  • preparation of scientific presentation and publication materials

Current status

The first documented reporting period was completed in 2026 and the reported work was accepted without objections. Further outputs will be added here as public materials become available.

Expected outputs

  • Structured in vitro toxicology data for environmentally relevant pollutants
  • Transcriptomic interpretation of exposure-related molecular response
  • Candidate molecular markers for qPCR validation
  • Conference presentation and scientific publication outputs

This project extends the laboratory’s environmental exposure work. See also: