27 November 2026 · Sofia · English · Hybrid seminar
All times are Sofia local time: EET (UTC+2), one hour ahead of CET. Convert the seminar start time to your time zone.
Why Shotgun Proteomics? From Focused Measurements to Proteome-Wide Discovery
10:00–10:45 · 45 minutes · Sofia local time
Dr. Goran Mitulović · Bio
Bruker Daltonics, Vienna, Austria
Why and when to use shotgun proteomics instead of focused or targeted protein analysis. Minimum requirements for sample preparation, LC-MS instrumentation, data acquisition and quality assessment. Opportunities to use or adapt existing mass-spectrometry infrastructure in Bulgaria.
Transcriptomics and Proteomics: From Omics Data to Biological Insight
10:45–11:30 · 45 minutes · Sofia local time
Dr. Thomas Mohr · Bio
ScienceConsult – DI Thomas Mohr KG; Department of Analytical Chemistry, University of Vienna; IMC University of Applied Sciences Krems, Austria
Comparison of transcriptomic and proteomic technologies, their information content, strengths and limitations, and the value of combining them. Introduction to quality control, normalisation, exploratory analysis, differential expression, statistical testing and multiple comparisons, functional enrichment, pathway and network analysis, and multi-omics integration.
Omics in Experimental Toxicology and Pharmacology: Applications and Opportunities in Bulgaria
12:00–12:45 · 45 minutes · Sofia local time
Assoc. Prof. Yordan Yordanov, PhD · Bio
Department of Pharmacology, Pharmacotherapy and Toxicology, Faculty of Pharmacy, Medical University – Sofia; Research Institute of Innovative Medical Science, Medical University – Sofia, Bulgaria
Experimental examples showing how omics can reveal mechanisms of toxicity and drug action, identify molecular responses and generate testable hypotheses. Overview of Bulgarian omics research and collaboration based on bibliometric analysis, including expertise, infrastructure and collaboration opportunities. Emerging applications in NAMs, mechanistic toxicology and regulatory science.
Omics, NAMs and Their Role in Public Health and Regulatory Toxicology
13:45–14:30 · 45 minutes · Sofia local time
Prof. Tzveta Georgieva, PhD, ERT · Bio
National Center of Public Health and Analyses, Sofia, Bulgaria
Current and emerging uses of omics and molecular evidence in public health, hazard identification, mechanistic assessment and regulatory toxicology. Opportunities and limitations in incorporating omics and new approach methodologies into regulatory and public-health practice.
Omics as a Tool in Modern Experimental Pharmacology and Drug Research
14:30–15:15 · 45 minutes · Sofia local time
Prof. Georgi Momekov, PhD, DSc · Bio
Faculty of Pharmacy, Medical University – Sofia, Bulgaria
How omics complements classical experimental pharmacology in studying mechanisms of drug action, therapeutic responses, toxicity and candidate compounds. Examples and perspectives for integrating molecular profiling with experimental pharmacological models.
From Available Technologies to Collaborative Omics Research
15:15–15:45 · 30 minutes · Sofia local time
Teaching faculty and participants
Moderated discussion of opportunities for sharing infrastructure and expertise, developing joint projects, and expanding omics approaches in Bulgarian toxicology, pharmacology and public-health research. Participants will be invited to discuss practical next steps and interdisciplinary collaboration.